Varieties of neuropathological disorders are caused by a perturbation of normal
developmental processes, resulting from insults by heterogeneous etiologic factors. These
factors trigger the sequence of molecular, biochemical, and morphologic alterations of the
brain, resulting morphologically and/or functionally abnormal brain. The resulting brain
contains basic components of the normal brain but is assembled in an abnormal way. The
developmental stage when the insults occur appears to largely dictate the outcome of the …